Search results for "African meningitis belt"
showing 3 items of 3 documents
2017
Summary Objectives Neisseria meningitidis is the major cause of seasonal meningitis epidemics in the African meningitis belt. In the changing context of a reduction in incidence of serogroup A and an increase in incidence of serogroups W and C and of Streptococcus pneumoniae , a better understanding of the determinants driving the disease transmission dynamics remains crucial to improving bacterial meningitis control. Methods The literature was searched to provide a multi-disciplinary overview of the determinants of meningitis transmission dynamics in the African meningitis belt. Results Seasonal hyperendemicity is likely predominantly caused by increased invasion rates, sporadic localized …
Atmospheric dust, early cases, and localized meningitis epidemics in the African meningitis belt: an analysis using high spatial resolution data.
2018
8 pages; International audience; Background : Bacterial meningitis causes a high burden of disease in the African meningitis belt, with regular seasonal hyperendemicity and sporadic short, but intense, localized epidemics during the late dry season occurring at a small spatial scale [i.e., below the district level, in individual health centers (HCs)]. In addition, epidemic waves with larger geographic extent occur every 7–10 y. Although atmospheric dust load is thought to be an essential factor for hyperendemicity, its role for localized epidemics remains hypothetic.Objectives : Our goal was to evaluate the association of localized meningitis epidemics in HC catchment areas with the dust lo…
The association between respiratory tract infection incidence and localised meningitis epidemics: an analysis of high-resolution surveillance data fr…
2017
AbstractMeningococcal meningitis epidemics in the African meningitis belt consist of localised meningitis epidemics (LME) that reach attack proportions of 1% within a few weeks. A meningococcal serogroup A conjugate vaccine was introduced in meningitis belt countries from 2010 on, but LME due to other serogroups continue to occur. The mechanisms underlying LME are poorly understood, but an association with respiratory pathogens has been hypothesised. We analysed national routine surveillance data in high spatial resolution (health centre level) from 13 districts in Burkina Faso, 2004–2014. We defined LME as a weekly incidence rate of suspected meningitis ≥75 per 100,000 during ≥2 weeks; and…